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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Unresectable Lung Non-Small Cell Carcinoma

Clinical Trial of AMG510 in Stage III Unresectable NSCLC KRAS p.G12C Patients and Ineligible for Chemo-radiotherapy NCT05398094Phase 220 sites๐Ÿ“ Alicante๐Ÿ“ Badalona๐Ÿ“ Barcelona Fundaciรณn GECP ยท Tests: Sotorasib A Prospective Phase II Clinical Study of Immunotherapy Combined With Chemotherapy for Stage III Unresectable Non-small Cell Lung Cancer NCT07082179Phase 21 site๐Ÿ“ Nanjing Jiangsu Cancer Institute & Hospital ยท Tests: Iparomlimab and Tuvonralimab combined with paclitaxel polymer micelles and Platinum (cisplatin/carboplatin) RGL-270 + ICI in Advanced NSCLC NCT07652125NA1 site๐Ÿ“ Guangzhou Guangdong Association of Clinical Trials ยท Tests: RGL-270 in Combination with PD-1/PD-L1 Inhibitors, Physician's Choice SOC Study of Antitumor Immune Response After cCRT and IO Treatment in Non-resectable III Stage NSCLC Patients NCT06634199n/a22 sites๐Ÿ“ Ferrol๐Ÿ“ Alicante๐Ÿ“ Badalona Fundaciรณn GECP ยท Tests: Durvalumab Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC NCT03872661Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: IBI308, Bevacizumab, Pemetrexed, Carboplatin, Thoracic surgery A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer NCT07250477Phase 24 sites๐Ÿ“ Chico๐Ÿ“ Marysville๐Ÿ“ Sacramento University of California, Davis ยท Tests: Systemic (ICI)-based therapy informed by the PROphet CB assay and the CARG-TT assessment., Standard of Care Firmonertinib Combined With Definitive Radiotherapy in Stage III Unresectable EGFR Uncommon Mutant Pulmonary Adenocarcinoma NCT07314216Phase 21 site๐Ÿ“ Changsha Hunan Cancer Hospital ยท Tests: Firmonertinib, Definitive Thoracic Radiotherapy Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer NCT06899126Phase 3246 sites๐Ÿ“ Anchorage๐Ÿ“ Fountain Valley๐Ÿ“ Los Angeles Daiichi Sankyo ยท Tests: Trastuzumab Deruxtecan, pembrolizumab, Pemetrexed, Platinum Chemotherapy A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569Phase 114 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Boston Alterome Therapeutics, Inc. ยท Tests: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors NCT06218914Phase 118 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach AstraZeneca ยท Tests: NT-112: Autologous, engineered T Cells targeting KRAS G12D, AZD0240: Autologous, engineered T Cells targeting KRAS G12D Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors NCT07589205Phase 11 site๐Ÿ“ Tianjin Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Drug: IBI3028 Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC NCT04686305Phase 191 sites๐Ÿ“ Duarte๐Ÿ“ Newport Beach๐Ÿ“ Orange AstraZeneca ยท Tests: T-DXd, Durvalumab, Cisplatin, Carboplatin, Pemetrexed Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC) NCT06667908Phase 244 sites๐Ÿ“ La Jolla๐Ÿ“ Farmington๐Ÿ“ New Haven Johnson & Johnson Enterprise Innovation Inc. ยท Tests: JNJ-90301900, Durvalumab, Concurrent Chemo/Radiation Therapy (cCRT), Concurrent Chemo/Radiation Therapy (cCRT): Carboplโ€ฆ Adjuvant Chemotherapy +/- Cemiplimab and Sequential Hypofractionated Radiotherapy in Unfit or Elderly Patients With Stage III Lung Cancer NCT06656598Phase 225 sites๐Ÿ“ Angers๐Ÿ“ Angers๐Ÿ“ Avignon Intergroupe Francophone de Cancerologie Thoracique ยท Tests: Carboplatin, Paclitaxel, Cemiplimab, Curative hypofractionated radiotherapy, Cemiplimab (maintenance) Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer NCT05136846Phase 12 sites๐Ÿ“ Duarte๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: Carboplatin, Durvalumab, Paclitaxel, Papaverine, Radiation Therapy A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer NCT07005102Phase 2, Phase 365 sites๐Ÿ“ Chandler๐Ÿ“ Duarte๐Ÿ“ Irvine AbbVie ยท Tests: Standard of Care, Telisotuzumab Adizutecan, Osimertinib (Osi), Cisplatin, Carboplatin A Phase III Study to Assess the Effects of Almonertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer NCT04951635Phase 31 site๐Ÿ“ Ji'nan Jiangsu Hansoh Pharmaceutical Co., Ltd. ยท Tests: Almonertinib, Placebo Almonertinib Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC NCT06709859Phase 21 site๐Ÿ“ Jinan Shandong Public Health Clinical Center ยท Tests: Afatinib plus chemotherapy as conversion treatment A Phase 2 Clinical Study of ABSK061 and ABSK043 NCT06632262Phase 221 sites๐Ÿ“ Guiyang๐Ÿ“ Guiyang๐Ÿ“ Shijiazhuang Abbisko Therapeutics Co, Ltd ยท Tests: ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer NCT05361174Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ Miami๐Ÿ“ Orlando Iovance Biotherapeutics, Inc. ยท Tests: IOV-4001 A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab IBI363 (PD-1/IL-2ฮฑ-bias) in Combination With Chemotherapy as Neoadjuvant Therapy in Initially Unresectable Stage III Non-Small Cell Lung Cancer NCT07408635Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: IBI363 + Chemotherapy A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors NCT04913285Phase 148 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ San Diego Pierre Fabre Medicament ยท Tests: KIN-2787, KIN-2787 and binimetinib Understanding New Cachexia Subtypes Through Observational Epidemiological Research NCT07776353n/a1 site๐Ÿ“ Pleasanton Kaiser Permanente ยท Tests: Biospecimen Collection, Computed Tomography, Electronic health record review, Medical Device Usage and Evaluation, Physโ€ฆ A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C
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