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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Unresectable Metastatic Colorectal Cancer

Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer NCT06509126Phase 31 site๐Ÿ“ Naples National Cancer Institute, Naples ยท Tests: Panitumumab, Irinotecan, 5-fluorouracil, L-folinic acid A Dose-Expansion Trial of Intravenous HNF4ฮฑ srRNA for Unresectable or Metastatic Colorectal Cancer NCT07050394EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: CD-GA-102 A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005Phase 17 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ St Louis Angiex, Inc. ยท Tests: AGX101 A Phase โ…ก/โ…ข Clinical Trial of RC148 Plus Chemotherapy as 1L Therapy for Unresectable or Metastatic Colorectal Cancer NCT07462143Phase 2, Phase 319 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing RemeGen Co., Ltd. ยท Tests: RC148 (Dose 1) plus Capecitabine and Oxaliplatin, RC148 (Dose 2) plus Capecitabine and Oxaliplatin Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer NCT06130826Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Bone Scan, Computed Tomography, Immunotherapy A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1) NCT07702032Phase 38 sites๐Ÿ“ Hot Springs๐Ÿ“ Los Angeles๐Ÿ“ Savannah Genmab ยท Tests: Petosemtamab, Cetuximab, FOLFIRI, mFOLFOX6 GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul GeneMedicine Co., Ltd. ยท Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) Conversion From Unresectable To Resectable Metastatic Colorectal Cancer. NCT03401294Phase 21 site๐Ÿ“ Regina University of Saskatchewan ยท Tests: FOLFOXIRI and Bevacizumab A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569Phase 114 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Boston Alterome Therapeutics, Inc. ยท Tests: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors NCT06218914Phase 118 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach AstraZeneca ยท Tests: NT-112: Autologous, engineered T Cells targeting KRAS G12D, AZD0240: Autologous, engineered T Cells targeting KRAS G12D COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases NCT06185556Phase 2, Phase 31 site๐Ÿ“ Amsterdam Amsterdam UMC, location VUmc ยท Tests: Irreversible electroporation, Stereotactic body radiotherapy Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors NCT07589205Phase 11 site๐Ÿ“ Tianjin Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Drug: IBI3028 A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer NCT04991948Phase 15 sites๐Ÿ“ Jacksonville๐Ÿ“ Tampa๐Ÿ“ Edegem Celyad Oncology SA ยท Tests: CYAD-101, FOLFOX, Pembrolizumab Study of a Tankyrase Inhibitor RK-582 for Patients With Unresectable Metastatic Colorectal Cancer NCT06853496Phase 11 site๐Ÿ“ Koto-ku Eiji Shinozaki ยท Tests: RK-582 Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH) NCT06938971NA4 sites๐Ÿ“ Copenhagen๐Ÿ“ Herlev๐Ÿ“ Hillerรธd Copenhagen University Hospital, Rigshospitalet ยท Tests: Exercise training Real World Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie NCT06808685n/a14 sites๐Ÿ“ Vitรณria๐Ÿ“ Curitiba๐Ÿ“ Londrina Libbs Farmacรชutica LTDA Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases NCT05248581n/a1 site๐Ÿ“ Rochester University of Rochester ยท Tests: Liver transplantation FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients NCT05727163Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Dexamethasone, Anisodamine, Oxaliplatin, Leucovorin, Fluorouracil Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases NCT02185443Phase 21 site๐Ÿ“ Sรฃo Paulo University of Sao Paulo ยท Tests: SBRT A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab Efficacy and Safety of Combined With Immunotherapy After Induction Therapy With Chemotherapy and Targeted Therapy in the First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer NCT06176885Phase 21 site๐Ÿ“ Jinhua yue junhan ยท Tests: Camrelizumab Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial NCT05863195Phase 362 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix ECOG-ACRIN Cancer Research Group ยท Tests: Bevacizumab, Capecitabine, Cetuximab, Computed Tomography, Floxuridine Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer NCT07042685Phase 21 site๐Ÿ“ Houston The Methodist Hospital Research Institute ยท Tests: Fruquintinib Combined With Chemotherapy DEBIRI Plus Chemotherapy vs. Chemotherapy Alone in Colorectal Cancer Liver Metastases NCT06555003Phase 31 site๐Ÿ“ Tehran Tehran University of Medical Sciences ยท Tests: Drug-Eluting Embolic Bead, Chemotherapy drug Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer NCT05959356Phase 23 sites๐Ÿ“ Foshan๐Ÿ“ Guangzhou๐Ÿ“ Guiyang Sun Yat-sen University ยท Tests: Cetuximab + Envafolimab + mFOLFOXIRI, Cetuximab + mFOLFOX6 Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer NCT06605430Phase 21 site๐Ÿ“ Saint Louis Park HealthPartners Institute ยท Tests: Medical Cannabis A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay
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