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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Upper Tract Urothelial Cancer

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma NCT05595408n/a1 site📍 Shanghai RenJi Hospital · Tests: Adjuvant chemotherapy, adjuvant immunotherapy Korean Prospective Upper Tract Urothelial Carcinoma Cohort NCT07452432n/a1 site📍 Seoul Samsung Medical Center · Tests: Peripheral blood collection for ctDNA analysis uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto NCT05874921n/a22 sites📍 Santa Monica📍 Gainesville📍 Miami UroGen Pharma Ltd. · Tests: Jelmyto (mitomycin) for pyelocalyceal solution Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs NCT06652022NA2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Systematic therapy combined with radiotherapy, Systematic drug treatment Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC NCT06598761n/a2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Immunotherapy+radiotherapy, surveillance alone Translational Cancer Observational Protocol NCT06169436n/a1 site📍 Milan IRCCS San Raffaele · Tests: Nephroureterectomy Single-Port RAS Using Da Vinci SP Surgical System for UTUC Patients NCT06987552NA1 site📍 Taipei National Taiwan University Hospital · Tests: Da Vinci SP Surgical System Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer NCT07673016n/a23 sites📍 Oceanside📍 San Diego📍 San Jose Convergent Genomics, Inc. Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma NCT06262516NA4 sites📍 Gainesville📍 Springfield📍 Cleveland Case Comprehensive Cancer Center · Tests: Nephroureterectomy, Lymph Node Dissection A Study of RC48-ADC Combined with JS001 for Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma NCT05917158Phase 21 site📍 Nanjing Jinling Hospital, China · Tests: RC48-ADC and JS001 Validation of a Circulating Tumor DNA Blood Test in Muscle-Invasive Bladder and Upper Tract Urothelial Cancer NCT07756437n/a1 site📍 Ghent AZ Sint-Lucas Gent Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) NCT04574960Phase 32 sites📍 Ottawa📍 Toronto University Health Network, Toronto · Tests: Gemcitabine, Cisplatin, Carboplatin Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer NCT05775471Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Biopsy, Biospecimen Collection, Enfortumab Vedotin, MR Urography, Nephroureterectomy A Comprehensive Prospective Assessment of the Physical and Biological Effects of Upper Tract Urothelial Cancer (UTUC) NCT05438537n/a1 site📍 Hong Kong Chinese University of Hong Kong Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA NCT06948552Phase 21 site📍 Detroit Henry Ford Health System · Tests: 5-Aminolevulinic acid Hydrochloride (Gliolan®) Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer NCT06356155Phase 22 sites📍 Ann Arbor📍 Philadelphia University of Michigan Rogel Cancer Center · Tests: Enfortumab vedotin, Pembrolizumab SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma NCT06822010Phase 21 site📍 New Brunswick Rutgers, The State University of New Jersey · Tests: Sequential Gemcitabine and Jelmyto Treatment (Gem/Jel) Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma NCT06124976Phase 2, Phase 38 sites📍 Vancouver📍 Winnipeg📍 Halifax Peter Black · Tests: ST-02 Liquid Biospy for Urinary Cancers NCT06116396n/a1 site📍 Milan IRCCS San Raffaele · Tests: Genetic analysis on isolated cells Non-invasive Urinary Genomics-Based Risk Assessment for Early Urothelial Carcinoma Diagnosis NCT07614594n/a1 site📍 Zhengzhou Henan Provincial People's Hospital Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer NCT04628767Phase 2, Phase 3258 sites📍 Kingman📍 Fort Smith📍 Little Rock National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Doxorubicin Hydrochloride Radical Radiotherapy Versus Radical Surgery for UTUC NCT06652009n/a2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Radical nephroureterectomy, Radical radiotherapy Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma NCT04865939Phase 31 site📍 Dallas University of Texas Southwestern Medical Center · Tests: sterile water irrigation, Gemcitabine Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin Identification NCT07888374n/a1 site📍 Shanghai Ruijin Hospital Radical Nephroureterectomy With vs Without Template Lymph Node Dissection in High-Risk Upper Tract Urothelial Carcinoma (T-LND UTUC) NCT07321210NA1 site📍 Tianjin Tianjin Medical University Second Hospital · Tests: Template Lymph Node Dissection, Selective Lymph Node Resection A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer NCT06774131Phase 379 sites📍 Homewood📍 Chandler📍 Queen Creek UroGen Pharma Ltd. · Tests: UGN-104 Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer NCT06120387n/a2 sites📍 Beijing📍 Beijing Xuesong Li · Tests: Radical surgery, Kidney sparing surgery+Postoperative radiotheray A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD) NCT06991868n/a1 site📍 Beijing Peking University First Hospital Adjuvant Radioimmunotherapy Compared With Adjuvant Chemotherapy for UTUC NCT06120374n/a3 sites📍 Beijing📍 Beijing📍 Beijing Peking University First Hospital · Tests: Radiotherapy, Chemotherapy, Immunotherapy
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