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Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

RecruitingPhase 2Ages 18 Years - anyAllUniversity of California, Los Angeles
NCT00695214 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients with OSA considering surgical treatment Exclusion Criteria: * Minors * Pregnant women * Patients unable to provide informed consent in English themselves * Prisoners * Allergy to propofol, soybean oil, egg lecithin or glycerol * Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)
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What it tests

  • Propofol sedation
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Where

1 site
UCLA Santa Monica Medical Center
Santa Monica, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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