The DC Cohort Longitudinal HIV Status Neutral Study

Treatment Cohort Inclusion Criteria: * Patient is receiving care for HIV at one or more of the twelve participating clinics in the DC Cohort. * Patient is either age 18 years or older, or seeks HIV care independently and is able to understand and sign informed consent. * Patient is a minor who is consented by a parent or legal guardian. Treatment Cohort Exclusion Criteria: * Patient is unable or refuses to provide informed consent. * Minor children ages 12 through 17 who are unaware of their HIV status Prevention Cohort Inclusion Criteria: Persons receiving any antiretroviral prescription without evidence of HIV or Hepatitis B infection * PrEP (e.g., TDF/FTC, Descovy, Apretude) * Combination ART indicative of nPEP in an HIV-uninfected person * Persons receiving an antiretroviral prescription indicative of DoxyPEP Doxycycline 200mg PO taken within 72 hrs of unprotected sexual encounter (or variations thereof where clearly not prescribed as a treatment course) * Test positive for ≥1 bacterial STI (positive gonorrhea (GC/NG) or chlamydia (CT) test or positive syphilis test requiring treatment within one year) * 2 bacterial STI (GC, chlamydia, syphilis) tests at 2 or more different encounters * 2 HIV tests at 2 or more different encounters * Patient requesting PrEP at their clinical visit * Patient requesting nPEP at their clinical visit * People who identify as injecting drugs Patients with a Z29.81 Encounter for HIV pre-exposure prophylaxis