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CEUS for Blunt Abdominal Trauma in Children

RecruitingPhase 4Ages 0 Years - 17 YearsAllChildren's Hospital of Philadelphia
NCT03490929 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Children with blunt abdominal trauma often get a CT as the first line imaging to evaluate for intra-abdominal organ injury. CT scans have some downsides with regard to radiation exposure, costs, and need for transport. Contrast enhanced ultrasonography has recently shown some promise as a way to detect intra-abdominal organ injury and may be able to replace the need for conventional CT scanning, without the need for ionizing radiation and the ability to be performed at the bedside.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Hemodynamically stable (defined as not needing massive transfusion protocol and not undergoing an emergent surgical procedure within the next hour) 2. History of or suspicion for blunt abdominal trauma 3. Abdominal CT ordered or obtained Exclusion Criteria: 1. History of allergic reaction to Lumason, sulfur hexaflouride, sulfur hexafluoride lipid microsphere components, or other ingredients in Lumason (polyethylene glycol, distearoylphosphatidylcholine (DSPC), dipalmitoylphosphatidylglycerol sodium (DPPG-Na), palmitic acid) 2. Co-existing penetrating abdominal trauma 3. Known congenital or acquired heart disease
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What it tests

  • Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON]
  • contrast-enhanced ultrasound
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Where

2 sites
Mayo Clinic
Rochester, United States
Children's Hospital of Philadelphia
Philadelphia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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