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Constitution of a Clinical, Neurophysiological and Biological Cohort for Chronic Sleep Disorders Responsible of Hypersomnolence

RecruitingNAAges 6 Years - anyAllUniversity Hospital, Montpellier
NCT03998020 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic sleep disorders result from multiple pathophysiological mechanisms and are often associated with severe hypersomnolence, responsible for major disability. Hypersomnolence may be secondary to sleep disturbances at night by sleep fragmentation, both overall in restless leg syndrome (RLS) or specific to slow or paradoxical sleep in parasomnias (sleepwalking, sleep behavior disorder). paradoxical). Attention-Deficit / Hyperactivity Disorder (ADHD) is another cause of secondary hypersomnolence, unsolved pathophysiology, leading to a major disturbance of alertness. More rarely, hypersomnolence may be primary (central hypersomnia), representing then the most severe form existing in humans. The best-known central hypersomnia is narcolepsy type 1 (NT1), affecting 0.02% of the population. It is thanks to the existence of well-characterized clinical, biological and neuropathological patient

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📋 Eligibility rules (as published)
Inclusion Criteria: * Have a complaint of chronic hypersomnolence on questioning, identified by a sleep specialist and requiring objective explorations in the Centre de Hypersomnias Rares, with or without a diagnosis of chronic sleep disorder according to the International Classification scale in force at the time of diagnosis * can be treated or not for chronic sleep disorder. * speak and understand french * should have a social security system * should not have infectious or inflammatory pathology Exclusion Criteria: * be private of liberty * live in medical institution * be a major protected by law * not have social security system * refuse to participate in protocol
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What it tests

  • scale of severity
  • blood sample
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Where

1 site
UH Montpellier
Montpellier, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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