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โ† Trials
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Diet Intervention Treatment for Active Ulcerative Colitis

RecruitingNAAges 18 Years - 75 YearsAllMount Sinai Hospital, Canada
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine if a sustainable non-elemental diet can be used as a probiotic tool to alter the dysbiotic microbiome found in individuals with ulcerative colitis and thereby decrease disease activity.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * โ€ข Females and Males between the ages of 18 - 75 years of age at the time of enrolment * Must have established diagnosis of UC by standard endoscopic, radiographic, or histological criteria * Must have active UC defined by having a Mayo score equal to or greater than 2 within two months prior to enrollment * Must have had \> 10cm involvement at some point in their disease history * FCP\>250 or active endo within 6 months * If a smoker, must not change smoking habits (frequency) during the course of the study * If receiving medical therapy, no baseline therapy change within 4 weeks of study initiation and no change during the course of the study Exclusion Criteria: * โ€ข Uncontrolled inflammation which will likely require surgery or escalation of therapy within 4 weeks of enrollment * Pregnant or lactating females * Allergy or intolerance to key or a great number food components of the study diet * Current NSAID use * Diagnosed with PSC * Using topical therapies or suppositories * Antibiotic use within 4 weeks of the study enrollment or during the study * Confirmed C. difficile infection within 3 months of recruitment; * Diagnosis of primary PSC; * Currently using topical therapies or suppositories * History of dysplasia or colorectal neoplasia.
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What it tests

  • UC intervention diet
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Where

1 site
Mount Sinai Hospital
Toronto, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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