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BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma

RecruitingPhase 1Ages any - anyAlliCell Gene Therapeutics
NCT04162353 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a phase I, interventional, single arm, open label, treatment study to evaluate the safety and tolerability of BCMA-CD19 cCAR in patients with relapsed and/or refractory multiple myeloma and plasmacytoid lymphoma.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Signed written informed consent; Patients volunteer to participate in the research * Diagnosis is mainly based on the World Health Organization (WHO) 2008 * Patients have exhausted standard therapeutic options * Systematic usage of immunosuppressive drug or corticosteroid must have been stopped for more than 1 weeks * Female must be not pregnant during the study Exclusion Criteria: * Patients declining to consent for treatment * Prior solid organ transplantation * Potentially curative therapy including chemotherapy or hematopoietic cell transplant * Prior treatment with BCMAxCD3 or CD19xCD3 bispecific agents
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What it tests

  • BCMA-CD19 cCAR T cells
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Where

2 sites
Peking University Shenzhen Hospital, China
Shenzhen, China
Chengdu Military General Hospital
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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