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Utrecht Prostate Cohort for Cancer Treatment Intervention Studies and Long-term Evaluation

Recruitingn/aAges 18 Years - anyMaleUMC Utrecht
NCT04228211 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Rationale: Prostate cancer is the most common cancer in men worldwide. Survival rates are high due to the typically non-aggressive nature of disease and effective treatments. Radical treatments such as surgery and radiotherapy often cause toxicity and long term side effects. Based on current available literature, the choice for primary therapy for clinically localised prostate cancer has a negative impact on cancer-specific quality of life (QOL). New interventional treatments are being developed. The investigators aim to build a multidisciplinary prostate cancer cohort which will serve as a multi-trial facility for interventional treatment studies. The Trials within Cohorts (TwiCs) design, also known as cohort multiple Randomized Controlled Trial design (cmRCT) will be conducted and as a prospective registry for assessment of long-term safety, performance and effectiveness new treatment

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years. * Patients with newly diagnosed histologically proven prostate cancer, referred for radiation treatment to the Radiotherapy Department of the UMC Utrecht or for prostatectomy, watchful waiting or active surveillance to the Urology Department of St. Antonius hospital or the Urology Department of the UMC Utrecht. * Informed consent - at least - for use of routinely collected clinical data and to fill out questionnaires. Exclusion Criteria: * Mentally incompetent patients. * Inability to understand the Dutch language.
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What it tests

  • Not listed
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Where

2 sites
St. Antonius Hospital
Nieuwegein, Netherlands
University Medical Center Utrecht
Utrecht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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