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โ† Trials
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Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma

Recruitingn/aAges 18 Years - anyAllThe Royal Wolverhampton Hospitals NHS Trust
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In plain words

What the trial is, and whether it could suit you

The outlook for patients with haematological malignancies remains challenging. It has been shown in some early cancer studies that a particular drug called Zn-DDC otherwise known as Imuthiol is highly toxic to cancer stem cells. Imuthiol has been intravenously used in clinical trials with an excellent safety record. Recent novel therapy and immunotherapy in haematological malignancies have improved outcome and survival but come with an increasing cost burden. Imuthiol could be an ideal affordable drug to study on it's own as well as in combination with other drugs in myeloma and other haematological malignancies. This may lead to potential combination therapies which will be very effective as well as affordable in the future. There is the need to look to see if this drug, Imuthiol and along with complementary drugs lenalidomide (Revlimid) and pomalidomide (Pomalyst) can help in haematolo

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients diagnosed with haematological malignancy - either myeloma or acute leukaemia * Patients must be 18 years or over * Patients must be willing and able to give informed consent Exclusion Criteria: * Pregnant patients will not be entered
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What it tests

  • Zn-DDC
  • Lanalidomide with Zn-DDC
  • Pomalidomide with Zn-DDC
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Where

1 site
The Royal Wolverhampton NHS Trust
Wolverhampton, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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