Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL)

Inclusion Criteria: * Patient over 18 years and less than 80 years old * Burned patients requiring at least one excision-graft surgery * Burn TBSA% between 5% and 40% * Signed informed consent or inclusion under the emergency provisions of the law (article L1122-1-2 of the CSP) Exclusion Criteria: * Proven severe allergy to cephalosporin or piperacilline-tazobactam or any other antibacterial agent of the penicillin class * History of severe allergic reaction to any other beta-lactam (eg cephalosporins, monobactams or carbapenems). * Patient on antibiotic therapy at the time of surgery * Pregnant or breast-feeding patient * Patient not covered by the social security * Patient transferred from another burn Unit * Patient participant in investigational competitive medicinal product study on the primary endpoint * Patient with local or systemic signs of infection requiring systemic antimicrobial therapy * Patient under guardianship * Patient under curatorship * known colonization of the burned area to be excised with tazocillin-resistant germ. * obese patient with BMI \> 50 kg/m²