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Hormone Replacement Trial Against ALzheimers' Disease

RecruitingNAAges 40 Years - 65 YearsFemaleUniversity Hospital, Ghent
NCT04312399 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The influence of postmenopausal hormone treatment on dementia is not clear. Dysfunctions in the metabolism of amyloid in the disease of Alzheimer result in an elevated presence of degradation products in cerebrospinal fluid. The degradation products in blood will be analysed during the trial, to get better insight in menopause and the start of hormonal therapy. Postmenopausal women with and without history of breast cancer will be recruited for the trial.

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📋 Eligibility rules (as published)
Inclusion Criteria: * postmenopausal women * 40 - 65 years Exclusion Criteria: * Longer than 10 years in menopause * thyroid dysfunction * hypertension * medical history of psychiatric comorbidity * Alcohol and/or drug abuse * medical history of neurologic symptoms with cognitive symptoms
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What it tests

  • blood take
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Where

1 site
Ghent university hospital
Ghent, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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