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RESting-state Functional MRI in Patients With Optic Neuritis for ANticipation of reCovEry

Recruitingn/aAges 18 Years - anyAllFondation Ophtalmologique Adolphe de Rothschild
NCT04448938 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

When patients arrive in the waiting room of the MRI department, patients will be given the briefing note explaining the purpose of the study and how it is going. During the consultation, the radiologist will check the inclusion and non-inclusion criteria, and will take the time to answer all of the patient's questions about the study. If the patient agrees to participate in the research, the investigating doctor will obtain his consent. The MRI examination will be performed on a 3T multi-parametric MRI. Compared to the standard protocol, patients will benefit from an additional sequence of f-mRI, called resting state, and performed before injection of gadolinium contrast agent. A consultation with an ophthalmologist will also be carried out the same day, at the Adolphe de Rothschild Foundation. During this visit, an OCT examination (optical coherence tomography), a visual field as well

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years of age * Clinical suspicion of optic neuritis * Benefiting from an MRI for exploration of optic neuritis * Affiliate or beneficiary of a social security scheme * Having received informed information about the study and having given their express consent to participate in the study Exclusion Criteria: * Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women) * History of amblyopia * Any pre-existing pathology leading to a decrease in vision (e.g. retinitis pigmentosa, AMD, etc.) * Patient benefiting from a legal protection measure
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What it tests

  • MRI
  • visual acuity
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Where

1 site
Fondation A De Rothschild
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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