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RecruitmEnt Assessed by eleCtRical Impedance Tomography

Recruitingn/aAges 18 Years - anyAllUnity Health Toronto
NCT04460859 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The RECRUIT study is a multinational, multicenter physiological observational study conducted by the PLUG working group. It is a single-day study (1.5-2 hours) associated with specific lung (de)recruitment maneuvers to verify the feasibility of measuring the potential for lung recruitment in mechanically ventilated patients with ARDS by electrical impedance tomography (EIT).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Intubated moderate and severe ARDS according to the Berlin definition (PaO2/FiO2 ratio \<= 200 mmHg) * Under continuous sedation with or without paralysis Exclusion Criteria: * Age \<18 years * Bronchopleural fistula * Pure COPD exacerbation * Contraindication to EIT monitoring (e.g. burns, pacemaker, thoracic wounds limiting electrode belt placement) * Hemodynamic instability (Systolic BP \< 75 mmHg or MAP \< 60 mmHg despite vasopressors and/or heart rate \< 55 bpm) * Attending physician deems the transient application of high airway pressures to be unsafe
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What it tests

  • Specific lung recruitment maneuvers
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Where

4 sites
Faculdade de Medicina da University São Paulo
São Paulo, Brazil
St. Michael's Hospital
Toronto, Canada
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
Vall d'Hebron University Hospital
Barcelona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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