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Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer

RecruitingNAAges 18 Years - 85 YearsAllRuijin Hospital
NCT04527861 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is designed to investigate long-term oncologic outcomes of single-incision laparoscopic surgery (SILS) compared to conventional laparoscopic surgery (CLS) for colorectal cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years \< age ≤85 years * Tumor located in colon and high rectum ( the lower border of the tumor is above the peritoneal reflection) * Pathological or highly suspected colorectal carcinoma * Clinically diagnosed cT1-4aN0-2 M0 lesions according to the 8th Edition of AJCC Cancer Staging Manual * Tumor size of 5 cm or less * ECOG score is 0-1 * ASA score is Ⅰ-Ⅲ * Informed consent Exclusion Criteria: * Body mass index (BMI) \>35 kg/m2 * The lower border of the tumor is located distal to the peritoneal reflection * Familial adenomatous polyposis (FAP) * Inflammatory bowel disease (IBD) * Multiple malignant colorectal tumors * Pregnant woman or lactating woman * Severe mental disease * Previous gastrointestinal surgery (except appendectomy ） * Emergency operation due to complication (bleeding, perforation or obstruction) caused by colorectal cancer * Requirement of simultaneous surgery for other disease * Simultaneous or metachronous multiple cancers with disease-free survival ≤ 5 years
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What it tests

  • Single-incision Laparoscopic Surgery
  • Conventional Laparoscopic Surgery
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Where

11 sites
The 940th Hospital of Joint Logistic Support Force of Chinese of PLA
Lanzhou, China
Shengjing Hospital
Shenyang, China
Liaoning Tumor Hospital & Institute
Shenyang, China
Shandong Provincial Hospital
Jinan, China
The General Hospital of Western Theater Command
Chengdu, China
Zhejiang Provincial People's Hospital
Hangzhou, China
Shanghai Cancer Center
Shanghai, China
Dongfang Hospital Affiliated to Tongji University
Shanghai, China

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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