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Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer

RecruitingNAAges 18 Years - 75 YearsAllCentre Henri Becquerel
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In plain words

What the trial is, and whether it could suit you

Post-operative concomitant radiochemotherapy is a treatment that is difficult to achieve for several reasons. First of all, and by definition, these patients have had recent surgery, most often accompanied by several weeks of hospitalization and weight loss. In addition, the functional recovery of feeding capacity is not always complete at the time of the start of irradiation. In addition, concomitant radiochemotherapy is responsible for very frequent radiomucitus which alters the feeding capacity of patients during treatment. In total, the rate of complete radiochemotherapy (3 cures of cisplatin administered) varies from 50 to 70% depending on the studies, which were carried out in selected populations within the framework of an experimental clinical trial and without distinguishing between positive and negative Human Papilloma tumours . In our experience, in a population with a very h

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female, over 18 and under 75 years of age, * Worl Health Organisation score \< 2, * Treatment for a localized squamous cell carcinoma of the head and neck for which a curative treatment by concomitant post-operative radiochemotherapy based on cisplatin is retained, * Having signed the informed consent, * Affiliate or beneficiary of a social protection scheme. Exclusion Criteria: * History of other neoplastic disease less than 2 years old or progressive, * History of radiotherapy for head and neck cancer, * Contraindications to cisplatin, * Pregnant or breastfeeding woman, * Protected major (under guardianship or curatorship), * Patient participating in a therapeutic study * Patient unable to understand the study for any reason or to comply with the constraints of the trial
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What it tests

  • optimised management
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Where

7 sites
CHU Amiens
Amiens, France
CH Beauvais
Beauvais, France
Clinique du Parc
Caen, France
Centre Guillaume le Conquérant
Le Havre, France
CHRU Lille
Lille, France
Centre Henri Becquerel
Rouen, France
CH Saint-Quentin
Saint-Quentin, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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