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Immunological Mechanisms of Rejection in Uterine Transplantation

RecruitingNAAges 18 Years - 45 YearsFemaleHopital Foch
NCT04615221 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of this study is to understand the mechanisms of rejection in uterine transplantation and to search for non-invasive markers of rejection. The biological samples necessary for our research have been or will be collected during procedures (biopsies, smears, vaginal swab, blood tests) carried out as part of the scheduled follow-up of patients. These will be samples whose collection is minimally or not invasive

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient going to or having received a uterine transplant OR Patient going to or having donated a uterus for a recipient included in the study OR Premenopausal woman to undergo gynecological surgery under general anesthesia: for 4 of them it was a hysterectomy and they must be under 45 years old, the other 6 must be under 38 years old. Exclusion Criteria (For witness): * Pregnancy in progress * Current infection * Cervical dysplasia * History of transplant or transfusion * Cancer or history of cancer * Menopause * Patient aged 38 or over for the 6 controls without hysterectomy, patient aged 45 or over for the 4 patients with hysterectomy. * Endometriosis
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What it tests

  • Specimens
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Where

1 site
Hopital Foch
Suresnes, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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