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Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences

RecruitingNAAges 18 Years - anyAllUniversity Hospital, Basel, Switzerland
NCT04819737 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of multiple sclerosis according to established international criteria * Steroid free period: \> 4 weeks * Participation in the Swiss MS Cohort (SMSC) study Exclusion Criteria: * . History of severe (other) neurological, internal or psychiatric disease with SC affection * MRI-related exclusion criteria (questionnaire): 1. Paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the SC) 2. Pacemaker 3. Claustrophobia 4. Pregnancy, lactation 5. Known hypersensitivity to gadolinium-based contrast media
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What it tests

  • SC MRI
  • patient questionnaire
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Where

1 site
University Hospital Basel, Department of Neurology
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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