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Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope

Recruitingn/aAges any - 9 MonthsAllCentre Hospitalier Universitaire Vaudois
NCT05058781 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g. cryptorchidism, hypospadias and micropenis in male infants and clitoral hypertrophy in female infants. Genetic, hormonal and environmental factors are implicated in DSD. Infants with congenital hypogonadism hypogonadotrope (CHH) can present with DSD. Evaluation of hormonal profile during minipuberty could be of great help to better characterize the etiology of DSD and CHH in particular. Our main objective is to study hormonal profile during the minipuberty of infants born with DSD or born from parents with CHH compared to controls.

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📋 Eligibility rules (as published)
Inclusion Criteria: * infants born with symptoms of DSD * infants born from parents with CHH Exclusion Criteria: * premature \< 35 weeks of gestation * male infants with high scrotal cryptorchidism
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What it tests

  • Not listed
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Where

1 site
Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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