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Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF

Recruitingn/aAges any - anyAllUniversity of British Columbia
NCT05200429 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study intends to investigate health trends and data in cystic fibrosis patients all across Canada that are receiving modulator treatment so researchers can determine if CFTR treatments are effective over a long period of time and if so, which treatments work best for each individual. The study will collect clinical data from routine standard of care, patient reported outcomes via survey data and samples for a biobank.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Prescribed a CFTR modulator therapy and planning to commence modulator therapy within 30 days OR planning to switch modulator therapies within 30 days * Participates in the Canadian Cystic Fibrosis Registry (CCFR) * Informed consent by participant, or parent/legal guardian or assent Exclusion Criteria: * Known contraindications to CFTR modulator therapy
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What it tests

  • Trikafta
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Where

2 sites
British Columbia Children's Hospital
Vancouver, Canada
St Paul's Hospital
Vancouver, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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