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Cortical Excitability in Cyclic Vomiting Syndrome

RecruitingNAAges 18 Years - 60 YearsAllUniversity of Pittsburgh
NCT05256160 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

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📋 Eligibility rules (as published)
Inclusion Criteria: * diagnosis of CVS Exclusion Criteria: * history of CVS (for healthy control population only) * psychosis or altered cognitive status * history of head injury, metal in the skull, stroke, or a history of seizures or a history of syncope (fainting or passing out) * implantable devices, such as a pacemaker or nerve stimulator * current use of the following medications or use of substances which are known to lower the seizure threshold: clozapine (Clozaril), chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day * pregnancy
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What it tests

  • TMS Paired-Pulse assessment of cortical excitability
  • Autonomic activity
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Where

1 site
University of Pittsburgh Medical Center
Pittsburgh, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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