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Neuroimaging Reveals Treatment-related Changes in DLD

RecruitingNAAges 48 Months - 71 MonthsAllUniversity of Cincinnati
NCT05268341 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.

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📋 Eligibility rules (as published)
Inclusion Criteria: * ages 48-71 months * average nonverbal intelligence quotient (IQ) * enrolled in participating center * typically developing (receptive and expressive language, social, articulation, other) * DLD for expressive grammar * typical oral motor function * typical social/pragmatics skills * average hearing thresholds * monolingual and native Standard English speakers * does not have any uncorrected vision challenges Exclusion Criteria: * receiving co-occurring speech-language or other intervention for communication * not MRI safe * special education placement of child based on ability or behavior
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What it tests

  • My Sentence Builder
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Where

6 sites
New Horizon Childcare
Cincinati, United States
Empower Learn Create INC
Cincinnati, United States
Cincinnati Children's Hospital
Cincinnati, United States
CWFF CHild Development Center
Cincinnati, United States
Wesley Education Center for Children and Families
Cincinnati, United States
University of Cincinnati
Cincinnati, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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