🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effect of Attentional Therapy on Post-traumatic Stress Disorder

RecruitingNAAges 18 Years - 60 YearsAllUniversity Hospital, Lille
NCT05331534 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder. We recently showed using eye-tracking evidenced two types of AB towards negative stimuli: a "physiological AB" found both in healthy and individual with PTSD, characterized by a stronger initial attentional engagement towards negative stimuli compared to neutral stimuli, as revealed by longer first fixation duration dwell time on negative pictures than on neutral pictures; a "pathological bias" observed only in individuals with PTSD and characterized by an heightened sustained attention towards negative stimuli once detected, which further increases with prolonged exposure. The present study aimed at assessing the effectiveness of an eye-tracking assisted attentional bias reduction therapy, targeting

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Understanding and able to express themselves in French * Giving informed consent, by dating and signing the study participation form * Having health insurance coverage * Normal or corrected to normal vision and hearing * DSM-5 PTSD criteria, assessed using the CAPS and PCL-5 Exclusion Criteria: * Minors or adults under guardianship, under judicial protection, persons deprived of liberty * Pregnant or breastfeeding women * Refusal to participate after being clearly and fairly informed about the study * Sensory, visual or auditory incapacity to participate in the study * Personal history of neurological disorder or current neurological disorder * Use of drugs other than tobacco and alcohol * Alcohol use on the day of experimentation * Personal history of psychiatric disorders or current psychiatric disorders other than anxiety, depressive, or trauma and stress disorders assessed at clinical interview and with MINI * Personal history of multiple trauma in childhood * Psychotropic medication treatment not stabilized over the past 4 weeks * MOCA \< 26 * Contraindication to prolonged exposure therapy
💊

What it tests

  • Eye-tracking assisted attention control training (ACTo)
  • Attention control training (ACT)
📍

Where

1 site
Hôpital Fontan 2
Lille, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy