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Reducing Pain From Wisdom Molar Extractions

RecruitingPhase 2Ages 18 Years - 64 YearsAllRutgers, The State University of New Jersey
NCT05335070 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years of age or older (up to 64 years) * Any demographic * ASA 1 and 2 (mild or absent systemic illnesses, deemed fit for undergoing dental extractions under intravenous sedation) * Not pregnant (as will not qualify to undergo procedure under intravenous sedation as part of routine standard-of-care) * Adequate mental ability to understand and provide informed consent * Has smart phone and internet connection Exclusion Criteria: * Age older than 64 years (because they are poor candidates for undergoing procedures under intravenous sedation) * Pregnant * Incapable of providing informed consent * Any systemic condition that renders the patient at higher risk for complications under intravenous sedation * Documented allergy to the dental local anesthetic * Inability to tolerate any of the commonly used pain medications such as combination opioids, acetaminophen (Tylenol®) or ibuprofen (Motrin® or Advil®) * Limitation in adequate mouth opening in presence/absence of pain
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What it tests

  • Temporo-masseteric Nerve Block
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Where

1 site
The University Hospital- Dental Clinic
Newark, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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