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โ† Trials
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Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels

Recruitingn/aAges 18 Years - 70 YearsAllUniversity of Maryland, Baltimore
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In plain words

What the trial is, and whether it could suit you

Acute normovolemic hemodilution (ANH) is performed as a blood conservation technique during surgical procedures with high risk for significant blood loss. It is done by taking out some of the patients blood before surgery actually begins and storing this blood inside of the operating room and giving it back to the patient at the end of surgery when most of the expected surgical bleeding has already occurred. This practice reduces the amount of bleeding that occurs after surgery and also reduces the amount of blood transfusions given to the patient after surgery. Transfusion of blood products from the blood bank may cause problems such as transfusion reactions and infections like hepatitis, and also increases cost. 3 meta-analyses and several smaller trials have shown improvement in blood transfusion rates with the use of ANH, however there is no evidence of improvement in other complica

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Elective Coronary Artery Bypass Graft Surgery * Age 18-70 years * Anticipated Cardiopulmonary Bypass Duration less than 2 hours * Weight greater than 70kg * Hemoglobin greater than 12 g/dL Exclusion Criteria: * Emergency and redo cardiac surgery * Renal insufficiency with serum creatinine greater than 1.25 mg/dL and/ or estimated GFR less than 60 mL/min/1.73 m2 * Heart Failure with EF \<40% * Hepatic disease * Pulmonary Disease, including pulmonary hypertension * Inherited or Acquired Bleeding Disease
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What it tests

  • ANH
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Where

1 site
University of Maryland Medical Center
Baltimore, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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