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Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

RecruitingPhase 3Ages 45 Years - 65 YearsAllTanta University
NCT05576818 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 45 and 65 years old * Both sexes * Patients with Parkinson's disease on dopamine replacement therapy * Modified Hoehn and Yahr stage, MHY 1-4 Exclusion Criteria: * Patients who are currently using or used antibiotics therapy in the preceding month * Patients who are currently using or used other probiotic products in the preceding two weeks * Patients scheduled to undergo GIT surgery or those underwent GIT surgery * Patients with Known allergy to probiotics * Patients receiving artificial enteral or intravenous nutrition * Patients with depression and/or psychosis * Patients taking antioxidant and/or anti-inflammatory medications * Patients with Hyperthyroidism * Patients with inflammatory condition and/or condition involving oxidative stress * Smokers * Modified Hoehn \& Yahr stage MHY 5
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What it tests

  • Lactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers
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Where

1 site
Tanta University
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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