🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

RESTORES Trial: RESToration Of Rehabilitative Function With Epidural Spinal Stimulation

RecruitingNAAges 21 Years - anyAllNational Neuroscience Institute
NCT05644171 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Spinal Cord Injury (SCI), being a devastating diagnosis, has little to no recovery which leads to a long-standing of debilitating impairment for affected patients. The NNI Neurosurgery team, together with our collaborators, are expanding our recruitment from our pilot trial named RESTORES: RESToration of Rehabilitative function with Epidural Spinal Stimulation. This study aims to investigate the feasibility of electrical stimulation via a spinal cord stimulator (SCS), which will be implanted into the study subjects, and advanced robotic neurorehabilitation to aid in improving neurological function in patients diagnosed with chronic SCI. An additional 15 patients on top of the 3 ongoing patients, male and female participants, above the age of 21 who have been diagnosed with the condition for more than a year will be recruited for this study over a 2-year period. Rehab sessions will take p

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
⦁ Inclusion Criteria For inclusion in the study, the potential patient has to fulfil all of the following criteria: 1. 21 years old and older 2. Chronic (greater than one year) motor complete (AIS classification A or B) SCI 3. Spinal injury between the levels of Cervical 2 (C2) to Thoracic 12 (T12) 4. Segmental reflexes that remain functional below the level of lesion 5. Able to perform the perioperative rehabilitation program as judged by the research team * Exclusion Criteria Potential patients will be excluded from the trial if they fulfil any of the following criteria: 1. Significant medical co-morbidities that would significantly increase the risk of the operation 2. Severe dysautonomia with systolic blood pressure fluctuation less than 50 or more than 200mmHg on tilt table testing 3. Painful musculoskeletal dysfunction, contractures, unhealed fractures, pressure sores, severe spasticity, and osteoporosis 4. Significant psychological issues or ongoing drug abuse 5. Pregnancy and lactating patients 6. Progressive spinal cord disease
💊

What it tests

  • RESToration Of Rehabilitative function with Epidural spinal Stimulation
📍

Where

1 site
National Neuroscience Institute
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy