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OMAR Opioid Use Disorder

RecruitingPhase 1Ages 18 Years - anyAllYale University
NCT05683184 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Able to provide informed consent * Male and female 18 years and older * DSM-5 diagnosis of opioid use disorder (for OUD group) * Physically healthy i.e., no clinically unstable medical conditions * Written informed consent and have capacity to consent and comply with study procedures Exclusion Criteria: * Current neuro-psychiatric illness or severe systemic disease (opioid use disorder is permitted in the OUD group). * Presence of ferromagnetic metal in the body or heart pacemaker * Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits * Are claustrophobic * Hematocrit values lower than 30
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What it tests

  • [11C]OMAR
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Where

1 site
Connecticut Mental Health Center, Clinical Neuroscience Research Unit
New Haven, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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