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Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis.

RecruitingNAAges 18 Years - 65 YearsAllFondazione Policlinico Universitario Agostino Gem…
NCT05983809 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Multiple sclerosis (MS) is a chronic, inflammatory and neurodegenerative disease of the central nervous system that often results in motor and/or cognitive impairment. Epidemiologically, the onset occurs between the ages of 20 and 40, with a peak around the age of 30. MS is an extremely heterogeneous disease in terms of signs and symptoms, both in terms of the neurological systems involved and the degree of impairment and severity. The most common symptoms include, among others, difficulty walking and lack of balance. The lack of stability and coordination reduces independence and mobility, predisposing people with MS to accidental falls and compromising mobility in daily life. Another symptom that characterises MS is cognitive impairment, which mainly alters information processing speed and short- and long-term memory. MS-related cognitive impairment is detectable at every stage of the

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📋 Eligibility rules (as published)
Inclusion Criteria: * Definitive diagnosis of multiple sclerosis according to McDonald criteria; * Age between 18 and 65 years; * Pyramidal or cerebellar system with a score ≥ 2 on the EDSS; * EDSS between 2 and 3; * Ability to stand without support for 60 seconds; * Stability of disease-modifying treatment and absence of clinical relapse of the disease for at least 1 year; * Cognitive ability to execute simple orders and understand the physiotherapist's instructions \[assessed by Token Test (score ≥ 26.5)\]; * Ability to understand and sign informed consent. Exclusion Criteria: * Significant visual impairment, defined by a visual system score ≥ 2 on the EDSS; * Presence of vestibular disorders unrelated to MS; * Presence of psychiatric disorders or severe cognitive impairment, i.e. a Mini Mental State Examination (MMSE) score \< 24 (15); * Presence of cardiovascular and respiratory disorders; * Inability to provide informed consent.
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What it tests

  • Technological rehabilitation
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Where

1 site
Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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