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Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer

RecruitingNAAges 45 Years - 75 YearsFemaleOhio State University Comprehensive Cancer Center
NCT05984888 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with BC. Many cancer survivors experience memory and brain function decline following chemotherapy which can last for years. A newer diet pattern, Mediterranean-DASH \[Dietary Approaches to Stop Hypertension\] Intervention for Neurodegenerative Delay (MIND), was shown to help with protecting brain functions. The MIND diet is high in anti-inflammatory nutrients (e.g., omega-3 polyunsaturated fatty acids (PUFAs), carotenoids, B-vitamins, and polyphenols) and limits the intake of brain-unhealthy foods (i.e., butter/margarine, cheese, red meat, fried foods, pastries, and sweets), which may help alleviat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Stage II-IV hormone receptor+, breast cancer diagnosis * Post-menopausal (defined as at least 1-year post menses, on ovarian suppression medication, or s/p oophorectomy) * Within 4 weeks before or 12 weeks after starting initial systemic therapies (e.g. chemotherapy, targeted therapies such as CDK4/6 inhibitors, endocrine therapy) * Ability to access and use internet resources, including video calls using Zoom platform * English speaking Exclusion Criteria: * History of dementia, stroke, traumatic brain injury, brain metastasis or other conditions that could lead to cognitive impairment * MIND diet score \>8 * Unwilling/unable to eat \>2 types of MIND food * Receiving insulin therapy for diabetes * Diagnosis of triple negative breast cancer * Unable to give informed consent.
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What it tests

  • MIND Diet Intervention Group
  • General Health Curriculum (GHC) Group
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Where

1 site
Ohio State University Comprehensive Cancer Center
Columbus, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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