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The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

RecruitingPhase 1Ages 21 Years - 65 YearsAllYale University
NCT06070649 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) diagnosis of Alcohol Use Disorder * Medically healthy * Ability to provide consent Exclusion Criteria: * Unstable medical conditions
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What it tests

  • 0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion
  • 0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion
  • 25 mg Diphenhydramine (5 min) + Normal Saline
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Where

1 site
Connecticut Mental Health Center
New Haven, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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