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ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study

RecruitingNAAges 18 Years - anyAllUmeå University
NCT06153888 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD. The length of HD is usually the same as the time of fluid removal while sometimes this may differ. There is no clear guideline. In previous research the investigator noted that the heart releases more NT-pro-BNP during HD in numerous of the patients. The present study aims to clarify if the speed of fluid removal during HD is a factor that may alter the release of cardiac markers during HD. If so the recommendations for the prescription of HD can be updated.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult HD patients with an intra-dialytic weight gain (IDWG) ≥2.5% of target weight over the long interval (3 days) prior to inclusion. * Patients need to be able to understand the study information * Patients need to be able to give consent. Exclusion Criteria: * Active systemic inflammatory state such as extensive malignancy or acute septic infection. * Uncontrolled hyperphosphatemia decided by the local routine of the physician (due to somewhat decreased efficacy of the low flux filter to eliminate phosphate)
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What it tests

  • Ultrafiltration rate
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Where

1 site
Region Vasterbotten, Norrlands Universitetssjukhus, Dialysen
Umeå, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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