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GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis

RecruitingNAAges 18 Years - anyAllImperial College London
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In plain words

What the trial is, and whether it could suit you

Individuals attending the hospital to undergo operations are at risk of developing blood clots in the legs, known as deep vein thrombosis (DVT). A clot in the leg can cause swelling, pain, and other long-term problems. If a clot in the leg breaks off and travels to the lungs, it can cause problems with the lungs' ability to move oxygen from the air into the blood and may be life-threatening. This is known as pulmonary embolism (PE). DVT and PE are known collectively as venous thromboembolism or VTE. The importance of preventing VTE in surgical patients is widely recognised, with two main strategies used: thinning the blood with regular injections and/or tablets and wearing elastic stockings to help stop blood from sitting in the leg veins where it can clot. Evidence for using elastic stockings to prevent VTE has recently been challenged. Additionally, there is a lack of evidence for th

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults (โ‰ฅ18 years of age) * Participants undergoing elective surgery; risk assessed as requiring EDPTP Exclusion Criteria: * Contraindications to EDPTP or GCS * Individuals requiring therapeutic anticoagulation e.g., anticoagulation for previous DVT * Known thrombophilia or thrombogenic disorder
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What it tests

  • Graduated compression stockings
  • No Graduated compression stockings
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Where

3 sites
North Bristol NHS Trust
Bristol, United Kingdom
Imperial College Healthcare NHS Trust
London, United Kingdom
University College London NHS Trust
London, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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