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Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions

RecruitingNAAges 21 Years - anyFemaleNational University Hospital, Singapore
NCT06284031 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aim To determine the feasibility and safety of 3 fractions of high dose rate (HDR) brachytherapy with interstitial needles for cervical cancer in the outpatient setting Primary objective To determine the clinical outcome (2-yr local control rate, loco-regional control rate, progression free survival and overall survival) Secondary objective To determine the long-term toxicities of this regimen based on CTCAE v5

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. 21 years old and above 2. Histologically proven squamous cell carcinoma, adenocarcinoma, adenosquamous or poorly differentiated cervical cancer 3. Clinically or radiologically stage IB - IVA cervical cancer based on TNM 8th Edition 4. ECOG performance status 0, 1, or 2 5. To complete external beam radiotherapy and brachytherapy in NUH 6. Written, voluntary informed consent 7. Patients must be accessible for follow up and management in NUH Exclusion Criteria: 1. Post operative cervical cancer cases 2. Pregnant or breastfeeding women
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What it tests

  • 3 fractions HDR brachytherapy
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Where

1 site
National University Hospital
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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