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Health Outcomes of Parents With Cystic Fibrosis-Aim 2

Recruitingn/aAges 18 Years - anyAllUniversity of Pittsburgh
NCT06296394 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators. The investigators will collect physical and mental health data to comprehensively evaluate the impact of parenthood in CF with widespread highly effective CFTR modulator use. The main hypotheses this study aims to examine are: H1: Parents with CF and moderate-to-severe depression have more rapid change in ppFEV1 (percent predicted forced expiratory volume in one second) versus those with mild or no depression. H2: Parents with CF who have more parental responsibility and/or stress have more rapid ppFEV1 (percent predicted forced expiratory volume in one second) change than those with less responsibility/stress H3: Parents using CFTR modulators have decreased ppFEV1 (percent predicted fo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with cystic fibrosis via sweat test or genotype analysis * Became a first-time parent (including foster parent, step parent, adoptive parent, or legal guardian) to a child under 5 years of age within the last 180 days Exclusion Criteria: * Undergone a lung transplant * Does not speak/read English or Spanish
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What it tests

  • Parenthood
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Where

18 sites
University of Alabama-Birmingham
Birmingham, United States
National Jewish Health
Denver, United States
Northwestern University
Evanston, United States
Indiana University
Indianapolis, United States
University of Kansas Medical Center
Kansas City, United States
Johns Hopkins University
Baltimore, United States
Massachusetts General Hospital
Boston, United States
Boston Children's Hospital/Brigham and Women's Hospital
Boston, United States

…and 10 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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