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Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease

RecruitingNAAges 0 Years - 18 YearsAllCentre Hospitalier Universitaire de Nice
NCT06300788 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy.

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📋 Eligibility rules (as published)
Inclusion Criteria: All groups : * Minor patients (\<18 years) * Patients of both sexes * Informed patients and parents who have signed the informed consent form * Patients affiliated to social security Control group : \- Patients with no particular pathology undergoing surgery and receiving a preoperative check-up CKD groups : * Patients on dialysis for more than 3 months, regardless of technique * Kidney transplant patients * Patients with CKD, whatever the cause Exclusion Criteria: * Progressive cancer or kidney disease * Treatments that may modify PPi concentration (e.g. bisphosphonates)
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What it tests

  • PPI and T50 dosing
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Where

1 site
CHU Nice - Hôpital de l'Archet 2
Nice, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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