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โ† Trials
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Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

RecruitingNAAges 18 Years - anyAllKaohsiung Medical University
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In plain words

What the trial is, and whether it could suit you

1. Compare the efficacies and safety of 14-day bismuth-amoxicillin-vonoprazan tiple therapy, 14-day vonoprazan dual therapy and 14-day rabeprazole triple therapy in the first-line treatment of H. pylori infection. 2. To investigate the impacts of antibiotic resistance of H. pylori as well as CYP3A4, CYP2C19 and IL-1B -511 genotypes of host on the eradication efficacies of anti-H. pylori treatments.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: (1) At least 18 years old. (2) Subjects infected with Helicobacter pylori. Exclusion Criteria: 1. Those who have ever received Helicobacter pylori sterilization treatment. 2. Those who are allergic to the drugs used in this research. 3. Those who have had stomach surgery. 4. Those with severe liver cirrhosis or uremia or malignant tumors. 5. Women who are pregnant or breastfeeding.
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What it tests

  • vonoprazan, amoxicillin, tripotassium dicitrate bismuthate
  • vonoprazan, amoxicillin
  • rabeprazole, amoxicillin, clarithromycin
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Where

1 site
Kaohsiung Medical University Hospital
Kaohsiung City, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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