AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease

RecruitingNAAges 18 Years - anyMaleUniversity of Trás-os-Montes and Alto Douro
💬

In plain words

What the trial is, and whether it could suit you

Peripheral arterial disease (PAD) is characterised as an atherosclerotic disease, most common in the lower limbs (aortoiliac, femoropopliteal, and infrapopliteal arterial segments), which causes a decrease in blood flow to the areas adjacent to and posterior to the affected area. Intermittent claudication (IC) is the most common symptom in this disease that appears with exertion and relieves with rest, causing fatigue, cramps, discomfort, or pain in the lower limbs due to limited blood flow to the affected muscles. Supervised physical exercise has emerged as the first line of intervention in improving the symptoms of intermittent claudication and disease progression, and in the last decade there has been an exponential increase in the use of wearable technologies to monitor dose-response. However, the approach used is still simplistic because it is not personalised. In other words, patie

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with clinically stable PAD; * An ankle-brachial index (ABI) between 0.41-0.90 at rest in one or both lower limbs; * Mild to moderate claudication, corresponding to Fontaine Stage IIa and IIb; * A history of ambulatory leg pain; * Ambulatory leg pain confirmed by treadmill test; * Able to provide written consent. Exclusion Criteria: * Noncompressible, calcified, tibial arteries (resting ABI ≥ 1.4); * Use of medication that could influence claudication (e.g. Cilostazol or Pentoxifylline) 3 months prior to investigation; * Previous intervention (e.g. balloon angioplasty, stenting, bypass, exercise programme); * Inability to walk on a treadmill at a speed of 3.2 km/h (2 mph); * Participation in the past 6 months in a clinical trial or exercise program; * Asymptomatic PAD determined from the medical history; * Exercise limited by factors other diseases or conditions than intermittent claudication; * Angina pectoris, congestive heart failure, chronic obstructive pulmonary disease, severe arthritis, or limb amputation.
💊

What it tests

  • Exercise
  • Usual care
📍

Where

3 sites
Hospital Centre Hospitalar de Trás-os-Montes e Alto Douro
Vila Real, Portugal
Research Centre in Sports Sciences, Health Sciences and Human Development
Vila Real, Portugal
University of Trás-os-Montes and Alto Douro
Vila Real, Portugal
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy