The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for Infraorbital Neuralgia

Inclusion Criteria: 1. Age between 18 to 75 years; 2. Paroxysmal or persistent stabbing pain in the distribution area of the infraorbital nerve and positive response to diagnostic block (1 ml of 2% lidocaine) prior to treatment; 3. NRS score≥7; 4. Scheduled for PRF treatment for IONa； 5. Signed informed consent. Exclusion Criteria: 1. Platelet count \<105\*109/L, ongoing anticoagulation therapy or antiplatelets treatment, coagulation disorders or bleeding disorders; 2. Severe cardiopulmonary or hepatorenal dysfunction; 3. Infection at the puncture site; . 4. Neuralgia secondary to tissue damage around the infraorbital foramen from causes such as maxillary sinusitis or tumor; 5. History of destructive treatments such as radiofrequency thermocoagulation, chemical ablation, infraorbital neurectomy, infraorbital nerve avulsion, etc; 6. History of mental disorders； 7. History of narcotic drug abuse; 8. Unable to cooperation.