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Pressure Pain Tolerance in Relation to Balance and Strength in Children

RecruitingNAAges 9 Years - 14 YearsAllAdly A Adam
NCT06529874 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age range range was 9-14 years old. * Could follow given instructions. * Children with Sickle cell anemia were medically stable, and take their medications regularly. * Children with Sickle cell anemia had experience of chronic pain that lasts more than 6 months. * All children with Sickle cell anemia have average weight, height, and body mass index based on their age percentiles. * All normal healthy children did not participating in regular sport activities, particularly including lower limb strengthening. Exclusion Criteria: * Defined cardiovascular or respiratory disorders. * Renal failure. * Myocardial infarction, mainly within last month. * Unstable angina. * Recent thoracoabdominal surgery. * Thoracic or abdominal aneurysm or current pneumothorax. * Painful vaso-occlusive crises. * Muscular contractures, Joints' stiffness, or deformities. * Neuromuscular problems i.e., myositis or peripheral neuropathy.
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What it tests

  • Pressure pain tolerance measurement using Digital Pressure Algometer
  • Balance assessment using HUMAC balance system
  • Lower limb muscular strength using Lafayette hand held dynamometer
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Where

1 site
El-Tahrir st.- in front of Ben El-Sarayat, Ad Doqi Al Giza, Giza Governate
Giza, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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