🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Diagnosis of Graft Pathology by TruGraf

Recruitingn/aAges 18 Years - anyAllUniversity Health Network, Toronto
NCT06557564 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to to identify different causes of liver diseases or damage in liver transplant patients and develop a machine learning algorithm as a non-invasive tool leveraging gene expression and patient clinical information to classify transplant liver diseases We will collect blood samples of the participants who had undergone or will undergo the liver biopsy as part of standard of care, and use this blood in TruGarf. TruGraf is a non-invasive test that measures differentially expressed genes in the blood of transplant recipients to rule out liver damage. Researcher will collect the biopsy result from the medical record and this will be compared with the TruGarf results.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. . Single-organ Liver transplant recipients 2. Male or female, age \> 18 years at the time of signing informed consent. 3. Willing and able to provide informed consent. 4. Patients will be undergoing liver graft biopsy (for any reason), or have had a liver biopsy within 48 hours of consent. Exclusion Criteria: 1. Repeat transplant 2. Recipient of multi organ transplantation 3. Any treatment for graft rejection such as IV steroids has been given before biopsy. 4. Targeted biopsies for diagnosis of malignancy.
💊

What it tests

  • TruGraf liver gene expression
📍

Where

1 site
Toronto General Hospital -UHN
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy