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Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

RecruitingNAAges 55 Years - anyAllVA Office of Research and Development
NCT06607913 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study involving Denver and Baltimore VAMC sites is to improve health through the detection and rehabilitation management of hospital-acquired weakness in those with CKD. The study goals include identifying and monitoring the optimal muscle assessment sites in clinical settings, examining how muscle health impacts length of hospital stay and physical resilience, and determining how home-based and supervised exercise comparatively addresses post-hospitalization physical resilience using performance tests a

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \> 55 years * Diagnosis of stage 3-4 CKD or an eGFR of \<45 mL/min/1.73m2 Exclusion Criteria: * Cardiovascular risk: Poorly controlled hypertension (\>160/100) * Coronary event in past 6 months * Class III or IV CHF * symptomatic angina at rest or during exercise * Syncope in past year, without known resolution of cause * COPD requiring home oxygen * Contraindications to resistance training, including history of intracranial or retinal bleeding; Diabetes with active proliferative retinopathy * History of significant spinal osteoarthritis or spinal stenosis * Dementia (on medical record review or mini-mental status exam score)
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What it tests

  • Exercise
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Where

2 sites
Rocky Mountain Regional VA Medical Center, Aurora, CO
Aurora, United States
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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