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Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

RecruitingNAAges 40 Years - 75 YearsAllTanta University
NCT06641206 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to anesthesia and local anesthetics. Given its potential for pain management, exploring DEX as a treatment for KOA could offer a new and promising approach.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients were not assigned for surgical intervention; * Patients were free of exclusion criteria Exclusion Criteria: * Patients were assigned for surgical intervention; * Patients who had uncontrolled hypertension and/or diabetes mellitus; * Patients who had uncompensated cardiac, renal, or hepatic diseases; * Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs; * Patients who refused to sign the informed consent were excluded from the study.
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What it tests

  • Triamcinolone Acetonide
  • Bupivacaine Hydrochloride
  • Dexmedetomidine
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Where

1 site
Tanta University
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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