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AI Model for Bone Mineral Density Prediction From X-Ray Images

Recruitingn/aAges 18 Years - anyAllBangladesh University of Engineering and Technolo…
NCT06652061 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Osteoporosis, a pervasive skeletal disorder characterized by diminished bone strength predisposing individuals to an increased risk of fractures, presents a substantial public health challenge globally. It's estimated that osteoporosis and its consequent increase in fracture risk significantly contribute to morbidity, mortality, and economic costs. Despite the availability of effective treatments, the condition often remains undiagnosed and untreated until a fracture occurs, underscoring the critical need for early detection and intervention. Dual-energy X-ray absorptiometry (DEXA) is the gold standard for assessing bone mineral density (BMD) and fracture risk. However, its utility is hampered by limited availability, especially in rural and low-resource settings, such as Bangladesh, where osteoporosis prevalence is notably high. The scarcity of DEXA units exacerbates the challenge of o

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📋 Eligibility rules (as published)
▪ Inclusion criteria: * Female and male patients aged 18 and above * Individuals willing to participate and who have provided informed consent for the use of their X-ray images and clinical data for research purposes. * Subjects with both X-ray images of hip and spine and DEXA scan results. * Accessibility to supplementary medical records that may contribute to the model's predictive accuracy, such as historical data on fractures, pregnancies, relevant medical conditions and other osteoporosis-related factors. * Exclusion criteria: * Subjects for whom X-ray images or clinical data are incomplete or of insufficient quality for analysis. * Individuals with medical conditions that could significantly alter bone density independently of osteoporosis, such as bone cancers or certain metabolic diseases. * Subjects who have undergone treatments or procedures that might significantly impact bone density measurement, such as long-term steroid use or recent orthopaedic surgeries. * Pregnant women, given the potential impact on screening results and the need for special considerations during pregnancy. * Patients with implant in hip or spine
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What it tests

  • Dual Energy X-Ray Absorptiometry Scan (DEXA Scan)
  • X-Ray (Hip and Spine)
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Where

1 site
Ibn Sina Diagnostic Centre, Uttara
Dhaka, Bangladesh
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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