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Research on Effects of Acute Consumption of Nuts in Obese Diabetic Women

RecruitingNAAges 18 Years - anyFemaleRaquel Ballarin
NCT06710340 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Obesity is a multifactorial disease in which excess body fat accumulation increases the risk of other chronic diseases such as type 2 diabetes. The primary cause of obesity is the energy imbalance between calories consumed and expended. A balanced diet is essential for weight control and maintaining a healthy body weight. In this context, the intake of a high saturated fat meal (HSFM) plays a detrimental role, contributing to the development of obesity, type 2 diabetes, cancer, cardiovascular diseases, and exacerbating chronic inflammation. Additionally, it may induce metabolic endotoxemia and modulate profiles of circulating microRNAs. Therefore, due to the harmful health impacts of HSFM, studies on metabolomics and circulating microRNA levels could enhance understanding of the mechanisms of walnuts (Juglans regia) in the prevention and treatment of diseases. The aim of this study is to

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women over 18 years of age * Diagnosis of obesity (body mass index \[BMI \>30 kg/m²\]) * Diagnosis of non-insulin-dependent type II diabetes Exclusion Criteria: * Use of dietary supplements or corticosteroid use in the last 3 months * Diagnosis of insulin dependent diabetes * Diagnosis of cancer * Diagnosis of heart failure * Diagnosis of kidney diseases * Diagnosis of liver diseases * Diagnosis of lung diseases * Diagnosis ofneurological diseases * Diagnosis of allergy to any component of the high saturated fat meal or walnuts
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What it tests

  • Nuts in the first meeting
  • Nuts in the second meeting
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Where

1 site
São Paulo State University (UNESP), Medical School, Botucatu
Botucatu, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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