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Antidiabetic Effect of Olive Pomace Oil

RecruitingNAAges 20 Years - 70 YearsAllInstituto de Ciencia y Tecnología de Alimentos y …
NCT06723886 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims at assessing whether consumption of olive pomace oil in the diet may benefit persons with type 2 diabetes mellitus or persons at risk of developing the disease (prediabetic persons). The main questions the study aims to answer are: * May olive pomace oil prevent a high increase of blood glucose levels when consumed in a meal together with carbohydrates in diabetic/prediabetic patients? * May olive pomace oil decrease fasting blood glucose levels of diabetic/prediabetic patients after consuming it daily? * May daily consumption of olive pomace oil improve glucose homeostasis and other alterations like elevated blood lipids or inflammation, which also affect persons with diabetes or prediabetes? Researchers will compare the effect of consuming olive pomace oil to the effects of a comparison oil (high-oleic acid sunflower oil). Participants will: In different d

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📋 Eligibility rules (as published)
Inclusion Criteria: * Fasting blood glucose between 100-126 mg/dL and/or * Glycated haemoglobin (HbA1c) between 5.7-6.4% and/or * Diabetic persons with Fasting blood glucose \>126 mg/dL and/or * Diabetic persons with Glycated haemoglobin (HbA1c) \> 6.4% Exclusion Criteria: * Kidney or liver diseases * Gastrointestinal diseases (irritable bowel syndrome, Crohn disease, chronic bowel inflammation) * Food allergies/intolerances * Vegetarians/vegans * Smoking * Pregnant or lactating women * On prescription drugs other than for hypertension/thyroid/dyslipidemia/glucose control, or changes in dosage in the last 3 months * Consumption of vitamins, dietary supplements or nutraceuticals
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What it tests

  • Experimental arm: Olive pomace oil
  • High-oleic acid sunflower oil
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Where

1 site
Institute of Food Science, Technology and Nutrition (ICTAN-CSIC)
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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