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Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study

RecruitingPhase 1Ages 18 Years - 65 YearsAllResearch Institute of Ophthalmology, Egypt
NCT06752486 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * patients over 18 years old * preoperative stable refraction for at least one-year, * normal corneal tomography with expected postoperative flat K reading not less than 38D, and postoperative residual stromal bed not less than 350 ฮผm. Exclusion Criteria: * Patients with preoperative corrected distance visual acuity (CDVA) of worse than 20/30 * amblyopic patients, * patients with a history of previous ocular surgeries, * herpetic eye infection, or corneal dystrophies. * Patients with other ocular conditions e.g. uveal or retinal diseases, and glaucoma * Diabetics, * Hypertensives, * Kidney problems, * breathing problems * Adults older than 65 years. * Previous allergy or adverse reaction to the used drugs. * History of drug abuse or alcohol abuse problems * History of mood problems, depression suicidal thoughts or behavior
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What it tests

  • Giving post photorefractive keratectomy for pain relief
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Where

1 site
Research Institute of Ophthalmolgy
Giza, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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