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Study on the Diagnosis of Ground-glass Lung Cancer by Microwave Ablation Combined With Puncture Biopsy

RecruitingNAAges 18 Years - 75 YearsAllBeidahuang Industry Group General Hospital
NCT06776588 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a multicenter study. It plans to screen 200 patients with pulmonary nodule lesions with ground glass as the main body, take CT thin-layer scanning 3D reconstruction, apply AI and fragment omics technology to evaluate the risk of malignant transformation of pulmonary nodules, and use microwave ablation to treat pulmonary nodules and combine intraoperative rapid pathology technology to determine the nature of puncture tissue and the degree of ablation, and then explore the optimal ablation time and ablation power.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≤ 75 years; 2. GGN patients with the maximum axial diameter of the lesion in the lung window ≤ 3 cm; 3. Refusing radical surgery or being unable to tolerate surgical treatment; 4. Normal coagulation function, platelet count ≥ 60 × 109 /L; 5. ECOG score ≤ 2 points; Exclusion Criteria: 1. Patients with the maximum axial diameter of the lesion in the lung window greater than 3 cm 2. Platelets \<50×109 /L 3. Patients with severe bleeding tendency and coagulation dysfunction that cannot be corrected in the short term 4. Severe chronic obstructive pulmonary disease, emphysema, pulmonary fibrosis and pulmonary hypertension 5. Patients whose anticoagulant therapy or antiplatelet drugs have been discontinued for less than 5 days before ablation 6. Patients with severe heart, liver, kidney and brain dysfunction 7. Patients with severe anemia, dehydration and cachexia that cannot be corrected or improved in the short term 8. Patients with an estimated survival period of less than 6 months
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What it tests

  • Microwave ablation combined with biopsy
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Where

1 site
Beidahuang Industry Group General Hospital
Harbin, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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