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Diagnosis and Treatment of Late Neurological Ischemic Deficit in Patients Suffering From Subarachnoid Hemorrhage.

Recruitingn/aAges 18 Years - anyAllFondazione IRCCS San Gerardo dei Tintori
NCT06804421 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Recent studies state that patients affected by aneurysmal subarachnoid hemorrhage (aSAH) today survive longer because they are treated early. Unfortunately, patients often develop chronic disabling neurological deficits at a rate that is still unacceptable given the progress in the specific treatment of this pathology and the volume of systems of neurological monitoring available to date in Italy. The main cause of unfavorable neurological outcome is delayed cerebral ischemia (DCI), often resulting from symptomatic vasospasm defined as delayed neurological ischemic deficit (DIND). The incidence of DIND is not defined and is difficult to diagnose early as there is no gold standard for identifying it, nor guidelines regarding the most effective treatment. Given these gaps, the primary objective of this study is to describe the incidence of DIND in patients affected by aSAH, collecting in

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Primary diagnosis of subarachnoid hemorrhage due to rupture of a cerebral artery aneurysm confirmed by cerebral angiotomography or angiography of the intracranial vessels, with the need for admission to the Intensive Care Unit * Signing the Informed Consent form to participate in the study according to current local regulations. Exclusion Criteria: * Age \< 18 years * Primary diagnosis of subarachnoid hemorrhage sine materia, i.e. post-traumatic or caused by arteriovenous malformation or bleeding from a brain tumor.
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What it tests

  • Not listed
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Where

33 sites
ASST Papa Giovanni XXIII
Bergamo, Italy
IRCCS Istituto delle Scienze Neurologiche
Bologna, Italy
ASST Spedali Civili
Brescia, Italy
Fondazione Poliambulanza
Brescia, Italy
ASST Lariana Ospedale Sant'Anna
San Fermo della Battaglia, Italy
ASST Cremona
Cremona, Italy
Azienda Ospedaliero-Universitaria Careggi
Florence, Italy
IRCCS Ospedale Policlinico San Martino
Genova, Italy

…and 25 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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